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Forbion leads Oversubscribed $60 Million Financing in AIRNA to Advance New Class of RNA Editing Medicines and Progress Best-in-Class AATD Program into the Clinic

July 31, 2024

Human Health

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  • Financing led by Forbion is the 10th investment by the firm’s Ventures Fund
  • The proceeds will advance product candidate for the treatment of alpha-1 antitrypsin deficiency (AATD) into clinical trials
  • Josh Brumm, General Partner at Forbion, to join AIRNA Board of Directors with Tim Lohoff, Forbion Senior Associate, appointed as Board Observer

Naarden, The Netherlands, July 31, 2024 – Forbion, a leading global life sciences venture capital firm with deep expertise in Europe, today announced that it has led the $60 Million financing of AIRNA, a biotech company pioneering RNA editing therapeutics to restore the health of patients with rare and common diseases. This brings the total Series A funding of AIRNA to $90 million.

The financing was led by Forbion with participation from Ono Venture Investment, Alexandria Venture Investments, and other new investors, as well as AIRNA’s existing syndicate, including ARCH Venture Partners and ND Capital. The proceeds from the Series A financing will be used to advance AIRNA’s lead product candidate into clinical trials and further develop AIRNA’s broad pipeline.

AIRNA has a differentiated approach to delivering life-changing outcomes for patients with AATD and other severe diseases. We are excited to support AIRNA’s exceptional management team and collaborate across continents to build a leading genetic medicines company.

Josh Brumm

Forbion General Partner

This Series A financing brings together a distinctive syndicate of investors to support AIRNA’s vision of transforming lives by realizing the therapeutic potential of base editing for the masses. We are focused on bringing our first drug candidate to the clinic next year, and advancing our platform to unlock targets that are inaccessible by other modalities.

Kris Elverum

President and Chief Executive Officer of AIRNA

AIRNA launched with backing from ARCH Venture Partners to create a new class of RNA therapeutics based on seminal research published by academic co-founders Thorsten Stafforst and Jin Billy Li. AIRNA is developing medicines to address a wide array of diseases with high unmet need through its RESTORE+TM platform, which optimizes oligonucleotide sequence, chemistry, and delivery for precise, efficient, and safe RNA editing. AIRNA’s first product candidate is a potential best-in-class treatment for alpha-1 antitrypsin deficiency (AATD), a genetic condition implicated in severe lung and liver disease.

The Company also announced the appointment of Josh Brumm, General Partner at Forbion, to its Board of Directors. Mr. Brumm was recently the CEO of Dyne Therapeutics, a Forbion portfolio company developing oligonucleotide-based medicines for patients with muscle diseases. Forbion Senior Associate Tim Lohoff, PhD has been appointed Board Observer.

For more information, please contact:

Forbion Investor Relations
Email: Robbert.van.de.Griendt@forbion.com
General Partner IR & Impact

Forbion Communications
Email: laura.asbjornsen@forbion.com
Head of Communications